The persistence of high body sodium in previously edematous patients with heart disease.
نویسندگان
چکیده
IN PATIENTS with heart disease the presence of edema is indicative of an increase in extracellular fluid volume. Since the sodium concentration of extracellular fluid is about 140 mEq. per liter, expansion of the extracellular space is accompanied by the accumulation of large quantities of sodium. The magnitude of sodium accumulation has been demonstrated through measurement of total exchangeable sodium in edematous cardiac patients by the sodiumisotope dilution technic.1-5 When edematous cardiac subjects are rendered free of edema, there is a marked drop in the body content of sodium,4 but one study showed that in over half of the cases the total exchangeable sodium remains either absolutely high or disproportionately high in terms of the body weight and total body water.' The present investigation was undertaken to re-examine the body composition of the cardiac patient without edema and in particular to determine whether the total body sodium remains elevated or eventually returns to normal levels. The data support earlier observations indicating that the majority of previously edematous cardiac patients have a body content of sodium that is absolutely or relatively high. In addition, the study showed that while some patients gradually lost their sodium excess over a period of months, others maintained a disproportionate elevation in body sodium as long as they were observed.
منابع مشابه
Exchangeable Sodium , Body Potassium , and Body Water in Previously Edematous Cardiac Patients
PREVIOUS STUDIES from this laboratory have indicated that cardiac patients who have been successfully treated for congestive heart failure and who have become free from edema have a larger than normal concentration of sodium in their bodies." 2 The suggestion was advanced that part or all of the sodium excess in such patients represented osmotically inactive cation because the patients studied ...
متن کاملExchangeable Sodium, Body Potassium, and Body Water in Previously Edematous Cardiac Patients: Evidence for Osmotic Inactivation of Cation.
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ورودعنوان ژورنال:
- Circulation
دوره 24 شماره
صفحات -
تاریخ انتشار 1961